CORDIS Project
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BacStar develops engineered bacteria to deliver therapeutic proteins directly into cancer cells. By designing multifunctional proteins that can penetrate cell membranes, the project aims to enhance the efficacy of bacterial cancer therapies and improve treatment outcomes.
Conventional cancer therapies have many limitations that could potentially be overcome using engineered tumour targeting bacteria as cancer therapeutics.
These bacteria have been shown to selectively grow in tumours where they can produce and deliver therapeutic biomolecules (proteins) extracellularly in the tumour microenvironment.
However, the delivery of these biomolecules into the cytoplasm of targeted tumour cells remains a challenge, limiting the clinical translation of these therapies.
Ba…
UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK
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United States, Seattle Wa
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
Finland, Kuopio
Type: SME
Activity type: Private for-profit entities (excluding Higher or Secondary Education Establishments)
SME: Yes
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