CORDIS Project
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B-SMART focuses on creating modular nanoparticles to deliver therapeutic RNA to the brain for treating neurodegenerative diseases. The project aims to manufacture these nanoparticles using a quality-driven approach and evaluate their effectiveness in pre-clinical settings.
The overall objective of B-SMART is: 1. to design modular nanoparticles, 2. to manufacture them via a quality-by-design protocol, 3. to achieve delivery of therapeutic RNAs to the brain and treat neurodegenerative diseases.
I.To design modular nanoparticles consisting of oan active RNA payloadoestablished (lipid-based), emerging (trigger-responsive polymer-based) or exploratory (extracellular vesicle-based) nanoparticlesoa targeting ligand consisting of the variable domain of heavy chain only a…
UNIVERSITAIR MEDISCH CENTRUM UTRECHT
Partner organizations (coordinator is shown above), with normalized type and CORDIS activity type. Guests see up to 4 partners.
UNIVERSIDADE DE SANTIAGO DE COMPOSTELA
Spain, Santiago De Compostela
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
Netherlands, Enschede
Type: SME
Activity type: Private for-profit entities (excluding Higher or Secondary Education Establishments)
SME: Yes
VLAAMS INSTITUUT BIOTECHNOLOGIE FLANDERS INSTITUTE FOR BIOTECHNOLOGY
Belgium, ZWIJNAARDE - GENT
Type: Research institute
Activity type: Research Organisations
SME: No
United Kingdom, Oxford
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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