CORDIS Project
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This project investigates the role of the protein hnRNP A1 in the processing of microRNAs, specifically focusing on its interaction with the microRNA precursor pri-miR-18a. The research aims to uncover the functional domains of hnRNP A1 and identify other microRNAs that depend on this protein for their processing, enha…
MicroRNAs (miRNAs) are small non-coding RNAs that negatively regulate gene expression of complementary mRNAs.
They have diverse unique expression patterns and have been implicate in a number of biological processes.
It has been shown that in many physiological and pathological conditions individual miRNAs are subjected to post-transcriptional regulation, both at the level of Drosha and/or Dicer processing.
The host lab has recently found that hnRNP A1, a protein implicated in many aspects of RNA…
MEDICAL RESEARCH COUNCIL
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