CORDIS Project
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This project seeks to create self-replicating polymersomes for drug delivery by synthesizing amphiphilic block copolymers within the vesicles. The goal is to enhance drug delivery efficiency and scalability through biocatalysis and light-responsive mechanisms.
Polymersomes, hollow polymer vesicles made from assembled amphiphilic block copolymers, are interesting systems for drug delivery as they can be synthesised to be biocompatible, biodegradable, and/or stimuli-responsive. A main limitation of all drug delivery vehicles is that they require multiple steps of synthesis and a posterior self-assembly process that generates low yields and high quantities of non-encapsulated waste, limiting industrial scalability.
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