CORDIS Project
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This project focuses on understanding the structure-activity relationships of glycosaminoglycans, specifically heparin and chondroitin sulfate, to modulate biological processes. It aims to automate the synthesis of these compounds for studying their interactions with proteins.
While heparin, a glacosaminoglycan (GAG) has served as an anticoagulant for more than 60 years, the structure-activity relationship of heparin and chondroitin sulfate for specific interactions with proteins are still poorly understood.
It has become evident that defined lengths and sequences or patterns are responsible for binding to a particular protein and modulating its biological activity.
Determination of the structure-activity relationships of heparins and chondroitins creates an opportun…
MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV
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