CORDIS Project
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This project investigates the role of Myc proteins in tumor development, focusing on their stabilization in cancer cells. It aims to uncover mechanisms for targeting Myc as a therapeutic strategy, particularly through its interaction with the Aurora-A kinase.
There is an intense interest in the function of human Myc proteins that stems from their pervasive role in the genesis of human tumors. A large body of evidence has established that expression levels of one of three closely related Myc proteins are enhanced in the majority of all human tumors and that multiple tumor entities depend on elevated Myc function, arguing that targeting Myc will have significant therapeutic efficacy.
This hope awaits clinical confirmation, since the strategies that are…
JULIUS-MAXIMILIANS-UNIVERSITAT WURZBURG
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