CORDIS Project
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The ATRACTIVE project investigates the structural dynamics of human serum transferrin and its interactions with bacterial receptors that capture iron. By exploring how these dynamics are influenced by iron binding and potential drugs, the project aims to enhance understanding of protein functions and their implications…
Structural dynamics define the transition from one protein state to another and are modulated by interactions with partners-ligands and/or chemical modifications.
They are important to control protein biological activity, govern protein evolution and their alteration can lead to diseases or death.
The long-term objective of ATRACTIVE is to understand protein structural dynamics, their regulation and how such dynamics diversify a conserved structural core to evolve in computing distinct functions…
FOUNDATION FOR RESEARCH AND TECHNOLOGYHELLAS
IDRYMA TECHNOLOGIAS KAI EREVNAS
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