CORDIS Project
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The AtheroCaSR project investigates the role of Calcium Sensing Receptor in cardiovascular disease among chronic kidney disease patients. It aims to explore how modulating this receptor can prevent vascular disorders while maintaining bone health, potentially leading to new therapeutic strategies.
The principal cause of death in chronic kidney disease (CKD) patients is cardiovascular disease (CVD).
Current therapies to treat vascular calcification (VC) and atherosclerosis, which mainly target mineralization and hyperlipidaemia, are not fully effective and have considerable limitations; therefore, additional mechanisms must be investigated.
In this respect, hyperphosphatemia is associated with CVD and mortality in CKD patients.
Recently, it has been demonstrated that phosphate inhibits Cal…
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CARDIFF AND VALE UNIVERSITY HEALTH BOARD
United Kingdom, Cardiff
Type: Public body
Activity type: Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)
SME: No
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