CORDIS Project
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This project investigates the role of a protein called connexin 30 in memory processes during sleep. It aims to understand how this protein influences neuronal activity and memory consolidation through a combination of experimental techniques.
It is believed that sleep plays an important role in memory consolidation.
In rodents, hippocampal neurons (place cells) selectively discharge when the animal is in a specific location in space.
During subsequent sleep, they are reactivated in the same order at 200Hz network oscillations known as ripples.
This timescale is optimal for synaptic plasticity underlying memory.
The host team (Rouach) has recently shown that connexin 30 (Cx30), a main gap-junction subunit in astrocytes, regulates exci…
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