CORDIS Project
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This project investigates the role of astrocytes in regulating energy balance and metabolism, particularly in relation to obesity and type 2 diabetes. It aims to understand how communication between astrocytes and neurons affects energy homeostasis using advanced genetic models.
Obesity and type 2 diabetes have been increasing during the last decades, becoming highly prevalent diseases in our society.
Until very recently, astrocytes and other glial cells have been traditionally known as supportive cells to neurons, but the host research group led by Prof.
Matthias Tschöp has recently reported that insulin receptors (IRs) in astrocytes regulate glucose delivery into the brain and lack thereof leads to a reduced response of glucose-induced suppression of food intake (Garc…
HELMHOLTZ ZENTRUM MUENCHEN DEUTSCHES FORSCHUNGSZENTRUM FUER GESUNDHEIT UND UMWELT GMBH
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