CORDIS Project
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This project investigates how glial cells, particularly astrocytes, influence circadian rhythms in the brain. By employing advanced techniques in molecular biology and neuroimaging, it aims to uncover the mechanisms behind the coordination of brain cell activities that regulate sleep-wake cycles and related disorders.
The human brain contains more than 100 billion cells, the majority being non-excitable glial cells, remarkably coordinated by an intrinsic clock that produce a circadian rhythm in their physiology and behavior.
Circadian alterations affect human performances, productivity and are associated to increased risk of human-error related accidents and to a variety of brain disorders (e.g. sleep disorders).
However, neuropharmacological R&D faces the lack of knowledge on how this clock signaling is hier…
FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA
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