CORDIS Project
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This project investigates the role of astrocytes in depression, focusing on how their dysfunction affects brain signaling and behavior. By studying genetically modified mice, the research aims to identify molecular pathways involved in depression and potential new treatment targets.
Depression is a debilitating psychiatric disorder that affects 1 in 7 people worldwide.
Despite coordinated efforts from researchers and clinicians alike, the neurobiological substrates of depression remain largely unknown.
As a result, therapeutic options against depression are inadequate.Using a valid preclinical model, I recently demonstrated that depression alters the molecular composition of astrocytes and the organization of extracellular matrix (ECM), an assembly of molecules that are pri…
DEUTSCHES ZENTRUM FUR NEURODEGENERATIVE ERKRANKUNGEN EV
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