CORDIS Project
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The ASTRALIS project explores intracellular signaling in astrocytes, focusing on how these brain cells respond to norepinephrine. By using advanced optical techniques, it aims to clarify the dynamics of signaling pathways and their implications for brain function and related disorders.
ASTRALIS proposes all-optical strategies to shed light on holes in our understanding of how intracellular signaling complexity, downstream of specific G protein-coupled receptors (GPCRs), is generated in the brain.
We focus on the understudied cells of the brain, astrocytes, which are highly interconnected but electrically silent, and signal through GPCRs and second messengers in response to norepinephrine (NE).
We use them as models to study whether intracellular signaling in vivo is governed e…
MAX DELBRUECK CENTRUM FUER MOLEKULARE MEDIZIN IN DER HELMHOLTZ-GEMEINSCHAFT (MDC)
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LOS ANGELES UCLA SANTA BARBARA UCSB DAVIS UCD RIVERSIDE UCR SAN DIEGO UCSD SANTA CRUZ UCSC IRVIN
United States, Berkeley
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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