CORDIS Project
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This research focuses on understanding the molecular mechanisms that reorganize chromosomes during the cell cycle, particularly at the chromosome periphery. By mapping proteins associated with this region and studying their roles, the project aims to reveal how these components contribute to chromosome structure during…
While chromosomes fill the nuclear space as decondensed chromosome territories during interphase, they are dramatically re-structured into compact rod-shaped rigid bodies during mitosis.
The aim of my work is to elucidate the molecular mechanisms underlying this cell cycle-dependent chromosome reorganization.
Unlike previous studies, I plan to focus on a yet poorly characterized chromosomal domain defined as ‘chromosome periphery’. I first plan to establish a detailed map of the proteins that ta…
INSTITUT FUER MOLEKULARE BIOTECHNOLOGIE GMBH
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