CORDIS Project
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This project focuses on developing new asymmetric organocatalytic reactions for synthesizing complex polycyclic compounds, specifically targeting biologically active molecules like alkaloids. By utilizing chiral amines to activate enones, the project aims to achieve enantioselective synthesis of compounds with potentia…
The intramolecular Diels-Alder reaction of 2-amino-furan derivatives is a powerful tool for the rapid synthesis of complex polycyclic compounds.
The reaction has been used as a key step in the preparation of biologically relevant molecules such as natural products and pharmaceuticals.
However, despite the great potential of this kind of Diels-Alder reaction, no catalytic asymmetric version has been reported so far.
During this Fellowship we wish to develop new, asymmetric, organocatalysed cyclis…
THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD
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