CORDIS Project
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This project seeks to develop new methods for C-H bond functionalization inspired by natural processes. By creating innovative iron catalysts and radical functionalization techniques, the research aims to transform inert carbon chains into valuable compounds for medicinal use.
The excision of C-H bonds from an aliphatic carbon chain to produce functionalized compounds is a general pathway in biosynthetic transformations for which there are no simple and mild laboratory substitutes.
Moreover, their source materials (like dioxygen) are abundant and have proved to be sustainable for millions of years.
This proposal targets the invention of new bioinspired processes for C-H oxidation, arylation and dehydrogenation.
To achieve this goal, invention of both new suprabiotic i…
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