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The ArtMetBio project develops innovative artificial metalloenzymes by combining synthetic and biological catalysts for eco-friendly synthesis. It focuses on optimizing these catalysts through directed evolution to enable new chemical reactions and applications in biocatalysis, particularly for producing valuable compo…
Artificial metalloenzymes have emerge as a fusion of synthetic and biological catalysts for environmentally friendly synthesis.
These hybrid catalysts are created by tethering a catalytic metal ion or cofactor to a protein scaffold.
Optimized artificial metalloenzymes have the potential to harness the advantages of both systems, inheriting the versatility of synthetic catalysts and the efficiency and robustness of enzymes.
New tools, however, are required to realize the potential of artificial m…
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