CORDIS Project
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This research investigates how the immune system interacts with mitochondria, focusing on their role in inflammation. By studying the immune response to intact and damaged mitochondria, the project aims to uncover mechanisms that distinguish these organelles from bacterial pathogens, with implications for understanding…
Mitochondria, the powerhouses of our cells, are remnants of a eubacterial endosymbiont.
Because mitochondria retain many hallmarks of their bacterial origin, they have recently been implicated in the etiology of systemic inflammatory response syndrome, a frequent cause of death in intensive care units.
Remarkably, mitochondria are immunologically inert under normal homeostatic conditions, raising the fundamental question: how does the immune system distinguish mitochondria from resemblant bacter…
AARHUS UNIVERSITET
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