CORDIS Project
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This project investigates the sex-determining mechanisms in malaria-causing parasites. By utilizing advanced transcriptomics, it aims to uncover the biological processes that lead to the formation of male and female gametocytes, which are essential for malaria transmission.
Malaria is caused by parasites of the genus Plasmodium.
Whilst the disease is caused by asexual parasites, only sexual forms are capable of transmitting the infection to mosquitoes.
Sexual forms arise from a small subset of blood-stage parasites which divert from the cycle of asexual replication and embark on a sexual developmental trajectory.
Targeting the small population of parasites transmitted to mosquitoes would provide a powerful malaria control method.
Although several genes have been fo…
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