CORDIS Project
Funding breakdown and partner intelligence are Premium
Sign in and upgrade to Premium for EU contribution totals, consortium analytics, OpenAlex research context, and AI summaries. · 0 consortium intelligence fields visible of 1
Start free • Cancel anytime • 14-day refund guarantee
This project explores the diverse functionalities of Argonaute proteins, which are crucial for RNA interference. By studying both eukaryotic and prokaryotic variants, the aim is to engineer new Argonautes for innovative genome editing applications, enhancing our understanding of their mechanisms and potential uses in b…
Argonaute nucleases are key players of the eukaryotic RNA interference (RNAi) system.
Using small RNA guides, these Argonaute (Ago) proteins specifically target complementary RNA molecules, resulting in regulation of a wide range of crucial processes, including chromosome organization, gene expression and anti-virus defence.
Since 2010, my research team has studied closely-related prokaryotic Argonaute (pAgo) variants.
This has revealed spectacular mechanistic variations: several thermophilic pA…
WAGENINGEN UNIVERSITY
Partner organizations (coordinator is shown above), with normalized type and CORDIS activity type. Guests see up to 4 partners.
Similar projects, consortium collaboration history, frequent partners, and OpenAlex research context.
Guests see up to 5 EuroSciVoc fields.
Guests see up to 5 topics.
Guests see up to 5 keywords.
