CORDIS Project
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This project investigates how sex hormones influence neuromuscular junctions, focusing on the role of androgen receptors in motor neuron stability. It aims to uncover molecular mechanisms that could lead to new treatments for neuromuscular diseases.
Motor functions implement evolutionary relevant and necessary actions, such as running and breathing.
They rely on electric impulses which produce muscle contractions through the neuromuscular junction (NMJ).
Sex-dependent features including hormone production and genetics influence neuromuscular pathophysiology, but the molecular players involved are unknown.Here, I will unravel how sex hormones shape and maintain NMJs by dissecting the unconventional signalling exerted by peripheral hormone re…
UNIVERSITA DEGLI STUDI DI PADOVA
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