CORDIS Project
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APTADEGRAD is focused on developing a new therapy for diabetic foot ulcers using aptamer-based Lysosome Targeted Chimeras (LYTACs). This innovative approach targets specific proteins involved in the healing process to improve recovery outcomes for patients suffering from this serious condition.
Diabetic foot ulcers (DFUs) a major complication of diabetes, occur in ~25% of patients, with a five-year recurrence rate of ~65% . DFUs often end in hospitalization, with limb amputations in up to 60% of cases . DFU related mortality is 5% within twelve months, rising to 42% after five years.
Despite high prevalence and its major impact on the quality of life, no effective treatment has been approved, so DFU remain a highly unmet clinical condition.APTADEGRAD aims at obtaining in vivo proof-of-…
Partner organizations (coordinator is shown above), with normalized type and CORDIS activity type. Guests see up to 4 partners.
Portugal, Braga
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
Belgium, Charleroi
Type: SME
Activity type: Private for-profit entities (excluding Higher or Secondary Education Establishments)
SME: Yes
Spain, Santiago De Compostela
Type: Public body
Activity type: Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)
SME: No
Spain, Santiago De Compostela
Type: Research institute
Activity type: Research Organisations
SME: No
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