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The AppSAM project focuses on harnessing specific enzymes to enable environmentally friendly methylation and alkylation reactions. By developing modular systems for both laboratory and biological applications, it aims to create sustainable methods for producing complex chemical compounds relevant to pharmaceuticals and…
AppSAM will unlock the synthetic capability of S-adenosyl¬methionine (SAM)-dependent methyltransferases and radical SAM enzymes for application in environmentally friendly and fully sustainable reactions.
The biotechnological application of these enzymes will provide access to chemo-, regio- and stereoselective methylations and alkylations, as well as to a wide range of complex rearrangement reactions that are currently not possible through traditional approaches.
Methylation reactions are of pa…
ALBERT-LUDWIGS-UNIVERSITAET FREIBURG
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