CORDIS Project
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This project aims to develop a novel antibody-based approach to manage thromboxane levels in patients at risk of cardiovascular events. By synthesizing a stable analogue of thromboxane, the project seeks to create antibodies that can effectively remove it from the bloodstream, potentially reducing the risk of heart att…
Cardiovascular disease is the leading cause of death in the developed world; in Europe it led to over 4 million deaths (47%) last year.
Platelets play an essential role in haemostasis and a critical role in thrombosis and cardiovascular disease.
Their activation by thromboxane is crucial for thrombus formation but this can lead to myocardial infarction or stroke.
Due to the important role of platelets in cardiovascular disease, patients at risk of thrombotic events are routinely prescribed anti-…
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