CORDIS Project
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This project explores the genetic mechanisms of malaria resistance in mosquitoes, particularly Anopheles gambiae. By mapping genetic variants and studying their effects on pathogen interactions, the research aims to enhance understanding of malaria and arbovirus transmission.
Malaria parasite infection in humans has been called “the strongest known force for evolutionary selection in the recent history of the human genome”, and I hypothesize that a similar statement may apply to the mosquito vector, which is the definitive host of the malaria parasite.
We previously discovered efficient malaria-resistance mechanisms in natural populations of the African malaria vector, Anopheles gambiae.
Aim 1 of the proposed project will implement a novel genetic mapping design to…
INSTITUT PASTEUR
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