CORDIS Project
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This project aims to enhance the understanding of angiogenesis, the formation of new blood vessels, by investigating the interaction between Notch and Hippo-YAP/TAZ signaling pathways. It combines experimental and computational methods to predict how these interactions regulate angiogenesis, potentially informing new t…
Our limited understanding of angiogenesis, the process leading to the formation of new blood vessels from pre-existing ones, hinders the design of new treatments for associated diseases such as cancer, ischemia, and diabetic retinopathy.
It is well established that sprouting angiogenesis involves a process of endothelial cell phenotype selection mediated by the interaction between vascular endothelial growth factor (VEGF) and Notch signalling.
Recently, it has been demonstrated that the Yes-asso…
TECHNISCHE UNIVERSITEIT EINDHOVEN
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United States, Boston Ma
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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