CORDIS Project
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This project investigates the role of the protein kinase M zeta in maintaining long-term potentiation, a process essential for memory. The research aims to uncover the molecular mechanisms by which this protein influences synaptic strength and memory persistence using advanced imaging and electrophysiological technique…
In recent years significant progress has been made into deciphering the initial triggering mechanisms responsible for the induction of synaptic strengthening.
Contrarily, very few studies address the question as to which cellular processes are responsible for the maintenance of LTP.
Recently, the protein kinase M zeta (PKMζ, an atypical protein kinase C) has taken center stage in the field of synaptic plasticity due to its unique role in the maintenance of LTP.
Among some of the most crucial obs…
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS
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