CORDIS Project
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This project focuses on developing new methods for activating unactivated C-H bonds in aliphatic amines, aiming to simplify the synthesis of complex molecules. It seeks to create diverse functionalized amine compounds with potential applications in medicinal chemistry.
The development of new chemical transformations based on catalytic functionalization of unactivated C-H bonds has the potential to simplify the synthesis of complex molecules dramatically.
Although some progress have been achieved in this emerging area, the selective transformation of aliphatic C-H bonds is still a challenge.
This proposal aims to develop a new platform for the direct activation of unactivated sp3 C-H bonds of aliphatic amines and to apply this novel C(sp3)-H functionalization t…
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