CORDIS Project
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This project investigates the biological mechanisms behind the persistence of chemoresistant Acute Myeloid Leukemia (AML). By studying the genetic factors that contribute to treatment resistance, it aims to improve understanding and treatment strategies for this complex disease.
Acute Myeloid Leukemia (AML), the most common leukemia diagnosed in adults, represents the paradigm of resistance to front-line therapies in hematology.
Indeed, AML is so genetically complex that only few targeted therapies are currently tested in this disease and chemotherapy remains the only standard treatment for AML since the past four decades.
Despite an initial sustained remission achieved by chemotherapeutic agents, almost all patients relapse with a chemoresistant minimal residual diseas…
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE
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