CORDIS Project
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This research investigates the dynamic behavior of G protein-coupled receptors, which play a crucial role in various physiological processes. By studying the influence of lipids and receptor interactions, the project aims to enhance understanding of their signaling mechanisms.
G protein-coupled receptors (GPCRs) are the largest family of transmembrane receptors in eukaryotes.
They bind a wide range of ligands, such as neurotransmitters, hormones, lipids and many others. GPCRs are the target of more than 30% of the drugs currently on the market, addressing neuropsychiatric, cardiovascular, pulmonary and metabolic disorders, cancer, obesity and AIDS.
The functional versatility of GPCRs cannot be explained by a simple two-state model of activation considering only an act…
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United States, Stanford
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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