CORDIS Project
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This project trains scientists to develop drugs that target allosteric sites on proteins, offering a new approach to drug design. By utilizing various experimental and computational techniques, the project aims to enhance drug selectivity and reduce side effects, potentially leading to more effective therapies.
Most current drugs are designed to bind directly to the primary active sites (also known as orthosteric sites) of their biological targets.
Allosteric modulators offer a powerful yet underexploited therapeutic approach.
They can elicit a richer variety of biological responses and, since they target less conserved binding sites, higher selectivity and less adverse effects may be obtained (Changeux, Drug Disc Today 2013).
This proposal aims to train a new generation of scientists in exploiting the…
BIOMEDICAL RESEARCH FOUNDATION, ACADEMY OF ATHENS
IDRYMA IATROVIOLOGIKON EREUNON AKADEMIAS ATHINON
Partner organizations (coordinator is shown above), with normalized type and CORDIS activity type. Guests see up to 4 partners.
Austria, Wien
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
Spain, Barcelona
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
CHARITE - UNIVERSITAETSMEDIZIN BERLIN
Germany, Berlin
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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