CORDIS Project
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This project evaluates the safety and efficacy of allopurinol as an additional treatment for neonatal hypoxic-ischemic encephalopathy, alongside hypothermia. It aims to improve outcomes for affected infants and develop biomarkers for neonatal brain injury.
Neonatal hypoxic-ischemic encephalopathy (HIE) is a major cause of death or long-term disability in infants born at term in the western world, affecting about 1-4 per 1.000 life births and consequently about 5-20.000 infants per year in Europe.Hypothermic treatment became the only established therapy to improve outcome after perinatal hypoxic-ischemic insults.
Despite hypothermia and neonatal intensive care, 45-50% of affected children die or suffer from long-term neurodevelopmental impairment.…
EBERHARD KARLS UNIVERSITAET TUEBINGEN
Partner organizations (coordinator is shown above), with normalized type and CORDIS activity type. Guests see up to 4 partners.
UNIVERSITAETSKLINIKUM TUEBINGEN
Germany, TUEBINGEN
Type: Research institute
Activity type: Research Organisations
SME: No
Germany, Dresden
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
Netherlands, Utrecht
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
Belgium, Leuven
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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