CORDIS Project
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This project focuses on a newly identified enzyme that regulates inflammatory responses. It aims to gather evidence for its therapeutic potential in treating inflammatory diseases by conducting tests on human cells and animal models.
Acute inflammatory processes are associated with infections as well as autoimmune flares at the basis of a variety of human diseases.
While the molecular components and the logic of pro-inflammatory program are relatively well understood, less is known about the molecular mechanism of resolution, governing the termination of inflammatory responses.
In the course of carrying out the i-FIVE ERC grant project plan, we identified a novel, secreted, soluble enzyme as a negative regulator of pro-infla…
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