CORDIS Project
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This project investigates the mechanisms of Parkinson's disease, focusing on lysosomal dysfunction and its role in cell death and protein aggregation. It employs both in vitro and in vivo models to explore the effects of aging and specific genetic mutations on disease progression.
Parkinson’s disease (PD) is a chronic progressive neurodegenerative disorder with no proven neuroprotective or neurorestorative therapy.
The most consistent risk factor for developing PD is increasing age. PD is a disease where substantial cell loss in the substantia nigra pars compacta occurs alongside the formation of Lewy Bodies (LB).
Although LB represent a pathological hallmark of PD, their mechanisms of formation and significance for the disease process remain unknown.In Specific Aim (SA)…
UNIVERSITE DE BORDEAUX
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France, BORDEAUX CEDEX
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
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