CORDIS Project
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This project focuses on developing stable and selective catalysts for olefin metathesis, specifically targeting cross metathesis reactions and exploring applications in chemical biology. By creating artificial metathesis enzymes, the project aims to enhance selectivity in reactions and enable tagging of biomolecules wi…
The introduction of stable and selective catalysts for olefin metathesis (OM) has considerably simplified the construction of double bonds.
Herein we propose to tackle two areas of the OM reaction that have received little attention.
First, we will address selectivity problems in an important type of OM reaction: metathesis cross-coupling or simply cross metathesis (CM).
Second, we will examine the potential applications of OM in chemical biology. OM has no biological counterpart and therefore i…
EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH
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