CORDIS Project
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The ADVaNCE project aims to improve toxicological assessments by developing a network of adverse outcome pathways. It seeks to better understand how chemicals can lead to complex health effects, such as liver cancer, through interconnected biological mechanisms.
The field of toxicology is evolving from purely descriptive to a highly data‐rich science.
To structure this large amount of data and in this way make the usage more effective for the safety assessors, the concept of adverse outcome pathways was established providing a means of understanding how chemicals induce adverse effects through their toxicity pathways and modes of action.
However, there are some doubts if the one initiating event - one adverse outcome relationship enforced on AOPs by the…
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