CORDIS Project
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This project aims to characterize the signaling pathways of adiponectin receptors, which are crucial for treating obesity-related diseases. It combines molecular and structural pharmacology to enhance drug discovery efforts.
The human kind is witnessing an escalation of obesity-related health problems such as cardiovascular diseases and type 2 diabetes. A recent groundbreaking study revealed adiponectin receptors (ADIPOR) as key targets for treating such obesity-related diseases.
Indeed, the modulation of this integral membrane protein by small molecules agonists ameliorates diabetes and prolongs lifespan of genetically obese rodent model.
Despite these exciting results and the importance of ADIPOR in human physiolo…
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE
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