CORDIS Project
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This project investigates the relationship between sleep quality and Alzheimer’s disease by using advanced neuroimaging techniques. It aims to understand how disruptions in sleep-wake regulation may influence the early stages of Alzheimer’s pathology, particularly focusing on brain regions affected by the disease.
The increased prevalence of Alzheimer’s disease (AD) in our ageing society constitutes an urgent, far-reaching public health concern.
In the worldwide effort to identify leverage points to prevent or delay the onset of AD, sleep has recently emerged as a potent modifiable factor to slow down the hallmark pathophysiological processes of the disease, namely amyloid-beta and tau protein accumulation together with neurodegeneration.
Crucially, the brain regions that regulate sleep and wakefulness ar…
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