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AdaptiveTarget aims to enhance crop improvement by developing a bioinformatic method for targeted long-read sequencing of complex genomic regions. This method will facilitate the study of genetic variation crucial for disease resistance in plants.
Genetic variation at resistance loci is crucial for sustained crop yield, given the challenges and increased pest and pathogen pressures resulting from a warming climate.
Despite recent advances in massively parallel sequencing, disease resistance loci and other complex genomic regions of great practical, economical and scientific importance remain challenging to study.
The severe limitations of current methods pose a major problem for fully understanding and harnessing genetic variation for cro…
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