CORDIS Project
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This project studies endothelial cell behavior in blood vessel patterning, which is essential for organ function and development. By using advanced imaging techniques, it aims to understand how blood flow influences endothelial cell dynamics and identify factors involved in vascular disorders.
The formation of a functional patterned (adaptation) vascular network is essential for development, tissue growth, and organ physiology.
Several human vascular disorders arise from the mis-patterning (maladaptation) of blood vessels, such as arteriovenous malformations, aneurysms, and diabetic retinopathy.
Blood flow is recognized as the main inducer for vascular patterning, yet very little is known about the molecular mechanisms that vascular patterning.C.
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INSTITUTO DE MEDICINA MOLECULAR JOAO LOBO ANTUNES
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