CORDIS Project
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This project investigates the potential of a compound that activates the ROR transcription factor to enhance the expression of FGF21 for treating acute pancreatitis. By assessing its effects in established animal models, the research aims to develop a new therapeutic approach that could improve patient outcomes and red…
Pancreatitis in humPancreatitis in humans is a cause of significant morbidity and mortality.
Acute pancreatitis events have increased worldwide over the last 20 years at an average annual percent change of 3% and the economic burden is growing (1).
Treatments for pancreatitis are currently limited.
The overall mortality rate in acute severe pancreatitis is 10-15%.
Thus, a specific treatment for pancreatitis is of great need.
Recent reports suggest that FGF21 can ameliorate acute pancreatitis in…
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