CORDIS Project
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The ACU-SERS project focuses on improving antibiotic dosing for sepsis patients through a fast and automated system that quantifies drug levels in biological samples. By integrating microfluidics and Raman spectroscopy, it aims to enhance treatment outcomes and reduce antibiotic resistance.
Sepsis is a leading cause of death in hospitals resulting in ~700k deaths in Europe each year.
Patients urgently require critical care and are admitted to an intensive care unit (ICU), where they are treated with antibiotics.
However, antibiotic dosing is inappropriate in ~50% of sepsis patients, causing poor clinical outcomes due to increased adverse events, (neuro)toxicity and contributing to antibiotic resistance.
Antibiotic dosing can be significantly improved through therapeutic drug monito…
TECHNICAL UNIVERSITY OF DENMARK DTU
DANMARKS TEKNISKE UNIVERSITET
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