CORDIS Project
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This project focuses on developing palladium-catalyzed methods for activating carbon-hydrogen bonds to create nitrogen-containing organic compounds. The goal is to enhance synthetic pathways for pharmaceuticals, addressing the need for efficient production in medicinal chemistry.
Transition-metal catalysed C-H activation is a powerful tool to functionalise and derivatize organic molecules at seemingly inert sites.
The strategy opens new efficient synthetic routes to existing molecules and provides access to novel ones.
Our aim is to develop palladium catalysed sp3 C-H activation technology for the synthesis of nitrogen heterocycles and for the derivatization of simple secondary amines to high value molecules.
Our proposal will address demand in the pharmaceutical industr…
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