CORDIS Project
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This research investigates the organization and regulation of genes within the eukaryotic nucleus, focusing on the dosage-compensated X chromosome in male fruit flies. By studying the assembly and function of a specific protein complex, it aims to uncover the mechanisms that maintain gene expression balance in dynamic…
Eukaryotic nuclei are organised into functional compartments, – local microenvironments that are enriched in certain molecules or biochemical activities and therefore specify localised functional outputs.
Our study seeks to unveil fundamental principles of co-regulation of genes in a chromo¬somal compartment and the preconditions for homeostasis of such a compartment in the dynamic nuclear environment.The dosage-compensated X chromosome of male Drosophila flies satisfies the criteria for a funct…
LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN
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