CORDIS Project
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This project focuses on understanding how antibody structures can be designed to enhance their ability to recognize specific proteins. By using computational modeling and experimental techniques, the aim is to create novel antibodies with improved specificity and functionality for applications in diagnostics and therap…
We propose to elucidate the structural design principles of naturally occurring antibody complementarity-determining regions (CDRs) and to computationally design novel antibody functions.
Antibodies represent the most versatile known system for molecular recognition.
Research has yielded many insights into antibody design principles and promising biotechnological and pharmaceutical applications.
Still, our understanding of how CDRs encode specific loop conformations lags far behind our understan…
WEIZMANN INSTITUTE OF SCIENCE
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