CORDIS Project
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This project focuses on developing new chemical reactions using chiral Brønsted acids to create complex azabicyclic structures. By utilizing N-acyl iminium ions, the research aims to enhance the efficiency and selectivity of these reactions, contributing to advancements in organic synthesis, particularly for natural pr…
We wish to develop new asymmetric Brønsted acid catalysed cyclisation reactions that will allow the efficient and highly enantioselective construction of azabicyclic structures from readily available starting materials.
This will constitute a new, powerful and broadly applicable organocatalytic asymmetric strategy to such target molecules.
Conceptually our proposal is to exploit the high reactivity of N-acyl iminium ions in cyclisation reactions within the asymmetric environment of an associated…
THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD
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