CORDIS Project
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The AAVEYE project aims to develop advanced gene therapy techniques for treating inherited retinal diseases like Retinitis Pigmentosa and Leber Congenital Amaurosis. By utilizing adeno-associated virus vectors, the project seeks to restore photoreceptor function and improve visual outcomes in affected patients.
The retina represents the visual sensory receptor of the nervous system (CNS).
Inherited diseases like Retintitis Pigmentosa (RP) and Leber Congenital Amaurosis (LCA), for which no therapies are available, are due to mutations in genes preferentially expressed in the photoreceptor cells of the retina.
Vectors derived from the adeno-associated virus (AAV) efficiently transduce the retina of animal models. AAV-mediated gene transfer reverts retinal pigment epithelium (RPE) defects and the safety…
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LONDON
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
Estonia, TARTU
Type: Company (for-profit)
Activity type: Private for-profit entities (excluding Higher or Secondary Education Establishments)
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