CORDIS Project
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This project aims to understand the alternative androgen synthesis pathway during human fetal development, particularly its role in sexual differentiation and disorders like congenital adrenal hyperplasia. It focuses on the unique function of the fetal adrenal gland in hormone production.
The differentiation of male and female phenotype is established at 7-12 weeks post conceptionem.
During this period, maintaining the appropiate intrauterine hormone environment is essential.
In contrast to other species, the regulation of human sexual differentiation is linked with the development of the adrenal cortex, as can be concluded from the disorders (virilization and adrenal insufficiency in the newborn) observed in patients suffering from congenital adrenal hyperplasia (CAH), one of th…
THE UNIVERSITY OF BIRMINGHAM
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