CORDIS Project
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The project focuses on developing synthetic foldamers that mimic the complex structures and functions of natural biopolymers. By creating artificial molecular containers, it aims to enhance molecular recognition capabilities for various organic substrates.
Nature has evolved ultimate chemical functions based on controlling and altering conformation of its molecular machinery.
Prominent examples include enzyme catalysis and information storage/duplication in nucleic acids.
These achievements are based on large and complex yet remarkably defined structures obtained through folding of polymeric chains and a subtle interplay of non-covalent forces.
Nature uses a limited set of building blocks – e.g. twenty amino-acids and four nucleobases – with speci…
LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN
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