CORDIS Project
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This project aims to determine the high-resolution structure of the influenza virus ribonucleoprotein complex, focusing on the interactions between the viral polymerase and nucleoprotein. By employing advanced imaging techniques, it seeks to enhance understanding of influenza's molecular biology, aiding in the developm…
Influenza is a major public health burden, with seasonal outbreaks contributing significantly to mortality worldwide, and the emergence of pandemic strains remaining an ever-present threat.
Influenza drug and vaccine conception efforts are aided by a thorough understanding of its molecular biology.A key aspect of the influenza lifecycle is the production of capped and poly-adenylated messenger RNA by the heterotrimeric influenza polymerase (FluPol).
Ground-breaking work performed by the Cusack l…
EUROPEAN MOLECULAR BIOLOGY LABORATORY
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